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Health News Results - 61

10 Nov
Gene Therapy Used for First Time to Correct Fatal Illness Before Birth

Gene Therapy Used for First Time to Correct Fatal Illness Before Birth

Doctors are hopeful that an innovative treatment performed before birth may help children born with the rare genetic, and often fatal, condition called Pompe disease.

A thriving Canadian toddler is evidence that treatment while still in the womb offers better outcomes.

23 Sep
Hints That Experimental Drug Might Curb a Form of ALS

Hints That Experimental Drug Might Curb a Form of ALS

People with a rare genetic form of ALS may benefit from extended use of an investigational drug, a new study shows.

The medication, tofersen, benefited patients with mutations of the gene SOD1. These mutations create a misfolded version of a protein, which leads to

19 Aug
Major Gene Study Spots DNA Tied to Autism, Other Disorders

Major Gene Study Spots DNA Tied to Autism, Other Disorders

More than 70 genes are very strongly associated with autism and more than 250 are linked to the condition, a major new genetic analysis has revealed.

The analysis is the largest of its kind ...

10 Mar
Science Brings Shortcut to Spotting 50 Rare Genetic Diseases

Science Brings Shortcut to Spotting 50 Rare Genetic Diseases

Scientists have developed a single test that can rapidly detect a collection of rare genetic diseases -- an advance they hope will shorten the "diagnostic odyssey" that people with these conditions can face.

The test diagnoses conditions known collectively as "STR-expans...

21 Feb
Early Trial Offers Hope Treating Rare 'Brittle Bone' Disease

Early Trial Offers Hope Treating Rare 'Brittle Bone' Disease

An experimental drug may help build bone mass in some adults with a rare brittle-bone disease, a small preliminary study suggests.

The disease is called osteogenesis imperfecta....

27 Jan
Did Your Gene Screen Turn Up Dangerous DNA? Study Finds Real Risk Is Low

Did Your Gene Screen Turn Up Dangerous DNA? Study Finds Real Risk Is Low

Most gene variants that have been labeled "pathogenic" may make only a small difference in a person's risk of actually developing disease, a new study suggests.

Scouring genetic data on more than 72,000 individuals,

28 Dec
New Clues to Sudden Unexplained Deaths in Young Kids

New Clues to Sudden Unexplained Deaths in Young Kids

Every year in the United States, a few hundred children die suddenly and without explanation. Now researchers have found gene variants that may contribute to some of those tragic deaths.

The hope, experts said, is that understanding the underlying mechanisms will eventua...

20 Dec
Highly Inbred, French Bulldogs Face Higher Odds for 20 Health Issues

Highly Inbred, French Bulldogs Face Higher Odds for 20 Health Issues

French Bulldogs are incredibly cute, sporting adorable snub snouts, big round heads, bright wide eyes and large bat ears.

Unfortunately, the physical traits that make them one of the most popular breeds in the United States and United Kingdom also saddle them with a host...

13 Dec
Could Gene Therapy Help Cure Sickle Cell Disease?

Could Gene Therapy Help Cure Sickle Cell Disease?

A gene therapy that could provide a permanent cure for sickle cell disease continues to show success through a third wave of patients, researchers report.

The therapy, LentiGlobin, restored normal blood function in 35 sickle cell patients who had the one-time procedure, ...

09 Dec
More Time Outdoors May Lower Risk of MS in Youth

More Time Outdoors May Lower Risk of MS in Youth

Children at risk for multiple sclerosis (MS) might find some protection from the disease by spending more time in the sun, a small study suggests.

Although MS is rare in children and young adults, those with relatives who have the condition have increased odds of develop...

18 Nov
Gene Therapy May Reverse Hurler Syndrome, a Rare and Severe Illness in Kids

Gene Therapy May Reverse Hurler Syndrome, a Rare and Severe Illness in Kids

Gene therapy might soon offer a new option for children with a rare genetic disorder that damages tissues throughout the body, researchers are reporting.

In a study of eight children with the condition, called Hurler syndrome, researchers found that the gene therapy was ...

08 Nov
Blood Test Looks at Patients' Whole Genome to Spot Rare Inherited Diseases

Blood Test Looks at Patients' Whole Genome to Spot Rare Inherited Diseases

Whole genome sequencing of blood samples improves detection of rare genetic conditions called mitochondrial disorders, British researchers report.

These disorders are inherited and affect about 1 in 4,300 people, causing progressive, incurable diseases.

Though they...

25 Oct
Why Are Cases of Pancreatic Cancer Rising in Young Women?

Why Are Cases of Pancreatic Cancer Rising in Young Women?

In his work with patients who have pancreatic cancer, Dr. Srinivas Gaddam was bothered by something that he was seeing.

"There are some patients that you can't stop thinking about because they've left a mark on you and you try your best to turn things around, but there's...

21 Oct
Ten Years On, Gene Therapy Still Beating Most Cases of 'Bubble Boy' Immune Disease

Ten Years On, Gene Therapy Still Beating Most Cases of 'Bubble Boy' Immune Disease

Nine of 10 patients with so-called "bubble boy" immune disease who received gene therapy about a decade ago are still disease-free, researchers report.

The gene therapy was developed at the University of California, Los Angeles (UCLA), to treat the rare and deadly immune...

11 Sep
Child Cancers Are Rare, But Here Are Signs to Look For

Child Cancers Are Rare, But Here Are Signs to Look For

Most parents want their children to live carefree lives, so a diagnosis of childhood cancer is devastating. Fortunately, pediatric cancers are rare.

Yet it doesn't hurt to be watchful for the warning signs, suggest experts in childhood cancer from Penn State Health....

06 Sep
Insights Into Genes Driving Epilepsy Could Help With Treatment

Insights Into Genes Driving Epilepsy Could Help With Treatment

Danish researchers have found genetic causes for epilepsy in half of children they studied and said half of those could be treated with targeted therapies.

That's the upshot of genetic testing of 290 children born between 2006 and 2011. Some had been diagnosed with epile...

16 Jul
A Better Test to Help Spot Glaucoma?

A Better Test to Help Spot Glaucoma?

Glaucoma is a leading cause of vision loss in older people, and early detection can bring better treatment. Now, researchers in Australia say their experimental genetic test for glaucoma can identify 15 times more people at high risk for the disease compared to a current gene...

01 Jul
Gene-Based Embryo Selection: Are 'Designer Babies' on the Horizon?

Gene-Based Embryo Selection: Are 'Designer Babies' on the Horizon?

The notion of parents picking out genetically perfect babies may seem like science fiction, but bioethicists warn in a new report that some companies have already started to offer couples going through in vitro fertilization (IVF) the means to pick better embryos through polyg...

30 Jun
Gene Differences Could Have Black Patients Undergoing Unnecessary Biopsies

Gene Differences Could Have Black Patients Undergoing Unnecessary Biopsies

A gene variant may be driving high rates of unnecessary bone marrow biopsies in Black Americans, researchers say.

The variant is responsible for lower white blood cell levels in some healthy Black people, the investigators said.

"We've essentially created this raci...

29 Jun
CRISPR Therapy Fights Rare Disease Where Protein Clogs Organs

CRISPR Therapy Fights Rare Disease Where Protein Clogs Organs

Early research suggests that CRISPR gene-editing technology may some day lead to dramatic relief for patients struggling with amyloidosis, a rare but serious disease that can trigger organ failure.

"There are many different types of amyloidosis," explained study author D...

30 Apr
Cancers Far More Common in Medieval Times Than Thought

Cancers Far More Common in Medieval Times Than Thought

Cancer might seem like a modern problem, but new research has revealed that it affected up to 14% of adults in medieval Britain.

University of Cambridge researchers used X-rays and CT scans to search for evidence of cancer inside skeletal remains excavated as part of an ...

23 Apr
No Genetic Damage to Kids of Those Exposed to Chernobyl Nuclear Disaster: Study

No Genetic Damage to Kids of Those Exposed to Chernobyl Nuclear Disaster: Study

There's no evidence of genetic damage in the children of parents who were exposed to radiation from the 1986 Chernobyl Nuclear Power Plant disaster in Ukraine, researchers say.

Several previous studies have examined the risks across generations of radiation exposure from...

25 Mar
Drug Shows Promise Against Rare Condition That Stunts Kids' Growth

Drug Shows Promise Against Rare Condition That Stunts Kids' Growth

A new medication may offer hope to children with achondroplasia, a rare bone growth disorder that causes very short stature coupled with disproportionate limb and trunk size.

The experimental drug is called vosoritide. By tamping down overactive growth plate signaling th...

22 Mar
Lab-Made Heart Valves Can Grow Along With Youngest Heart Patients

Lab-Made Heart Valves Can Grow Along With Youngest Heart Patients

Lab-created heart valves that grow with the recipient could spare kids born with heart defects from the repeated valve-replacement surgeries they now endure.

University of Minnesota researchers found that lab-created valves implanted in young lambs for a year were capabl...

28 Jan
Early Promise for Therapy Against Duchenne Muscular Dystrophy

Early Promise for Therapy Against Duchenne Muscular Dystrophy

An experimental gene therapy for Duchenne muscular dystrophy shows promise, a small study suggests.

The severe form of muscular dystrophy -- which affects about one in 3,500 males born each year in the United States -- causes muscles to progressively weaken and lose the ...

15 Dec
Sickle Cell Puts Black Patients at Higher Risk for Severe COVID

Sickle Cell Puts Black Patients at Higher Risk for Severe COVID

Sickle cell disease increases the risk of death or serious complications from COVID-19 infection, a pair of new studies suggests.

People with sickle cell disease -- a genetic blood disorder predominantly found in Black people -- are 6.2 times more likely to die from COVI...

11 Dec
Gene Therapy Shows No Long-Term Harm in Animals: Study

Gene Therapy Shows No Long-Term Harm in Animals: Study

Results from a long-term study of a gene therapy technique to prevent inherited mitochondrial disease show promise, researchers say.

Studies of the technique at Oregon Health & Science University in Portland show no adverse health effects in rhesus macaque monkeys and th...

05 Dec
Could Gene Therapy Cure Sickle Cell Disease? Two New Studies Raise Hopes

Could Gene Therapy Cure Sickle Cell Disease? Two New Studies Raise Hopes

A pair of new gene therapies promise a potentially lasting cure for sickle cell disease by subtly altering the genetic information in patients' bone marrow cells, researchers report.

Both therapies work by switching on a gene that promotes production of fetal hemogl...

03 Dec
Birth Defects Tied to Rise in Lifelong Cancer Risk

Birth Defects Tied to Rise in Lifelong Cancer Risk

Major birth defects are associated with an increased, lifelong risk of cancer, researchers say.

It has been known that people with major birth defects have a greater risk of developing cancer as children and teens, but it wasn't clear whether the risk extends into adulth...

15 Oct
Many Male Breast Cancers Diagnosed Late, and Delays Can Be Lethal

Many Male Breast Cancers Diagnosed Late, and Delays Can Be Lethal

Breast cancer in men is rare. But because it's not often suspected in men, diagnosis often comes only after a tumor has begun to spread throughout the body, new research shows.

"Approximately one-half of males with breast cancer received a diagnosis after it had alre...

17 Sep
Mother and Son Draw Hope, Healing From Shared Cancer Treatment

Mother and Son Draw Hope, Healing From Shared Cancer Treatment

Families bond over lots of shared experiences -- but one Leslie Seigel and her adult son, Josh, never expected to share was battling cancer.

Soon after Leslie finished chemotherapy for an aggressive form of breast cancer, however, Josh found himself waging his own ba...

16 Sep
New Research Links Another Gene to Alzheimer's Risk

New Research Links Another Gene to Alzheimer's Risk

A genetic variant in some people may be associated with mental decline that can't be explained by deposits of two proteins linked with Alzheimer's disease, researchers say.

They said their findings could lead to new treatments for Alzheimer's.

The two prote...

12 Aug
Genetic Research May Help Identify Causes of Stillbirth

Genetic Research May Help Identify Causes of Stillbirth

Scientists are well on the way to understanding more about how genes can cause stillbirth, new research suggests.

In the study, researchers used genetic analyses to identify gene mutations that are linked to stillbirth, which is the in utero death of a fetus after ...

16 Jul
More Clues to the Genes Behind Hearing Loss

More Clues to the Genes Behind Hearing Loss

Dutch researchers have identified a common genetic variant as a cause of deafness, and say it could be a good target for gene therapy.

Deafness in adults is known to be inherited but, unlike childhood deafness, the genetic causes aren't clear.

To date, 118 ...

27 May
Alzheimer's Gene Linked to Severe COVID-19 Risk

Alzheimer's Gene Linked to Severe COVID-19 Risk

People who have a flawed gene linked to Alzheimer's disease may face a higher risk of COVID-19, an international team of researchers reports.

Part of the increased risk among people with dementia may owe to high rates of new coronavirus infections in nursing homes. B...

30 Mar
Do Gene Mutations Explain COVID-19 Cases in the Young?

Do Gene Mutations Explain COVID-19 Cases in the Young?

Genetic mutations that put some younger people at high risk for severe illness from the new coronavirus will be investigated in an international study.

Plans call for enrolling 500 patients worldwide who are under age 50, have been diagnosed with COVID-19 and admitte...

20 Feb
How 'Stranger Things' Widened Awareness of a Rare Disorder

How 'Stranger Things' Widened Awareness of a Rare Disorder

Teenage actor Gaten Matarazzo III was born with a rare genetic disorder that affects bone development. And ever since his Netflix series "Stranger Things" became a hit, public interest in the condition has shot up, a new study finds.

The disorder, called cleidocrania...

06 Feb
Gene Variant Ups Dementia Risk in Parkinson's Patients: Study

Gene Variant Ups Dementia Risk in Parkinson's Patients: Study

A genetic variant associated with Alzheimer's disease increases the risk of dementia in people with Parkinson's disease, researchers say.

The finding could lead to new treatments for dementia in Parkinson's patients, according to the team at Washington University Sch...

06 Feb
Gene Variation May Protect Against Alzheimer's: Study

Gene Variation May Protect Against Alzheimer's: Study

A breakthrough study has identified a class of natural gene variants that may protect against Alzheimer's disease.

For the study, researchers at University College London analyzed DNA from more than 10,000 people -- half with Alzheimer's and half without. The investi...

05 Feb
New Gene Study Unravels Cancer's Secrets

New Gene Study Unravels Cancer's Secrets

Cancer is a genetically driven disease, and a mother lode of new genetic data on dozens of different cancers is promising to break open fresh avenues of prevention and treatment.

Nineteen out of 20 cancers now can be tracked back to one or more specific genetic mutat...

10 Jan
Veterans' Study Shows Genetic Origins of Anxiety

Veterans' Study Shows Genetic Origins of Anxiety

New research involving the DNA of 200,000 U.S. veterans suggests that there really is such a thing as a "worry gene."

Researchers have identified six genetic variants linked to anxiety -- a discovery that may help explain why anxiety and depression often go hand in ...

21 Nov
'Designer Babies' a Long Way Off

'Designer Babies' a Long Way Off

"Designer babies" aren't going to be a reality anytime soon, researchers say.

Concerns about genetically altering embryos to have desired traits have been around nearly as long as in vitro fertilization (IVF) and the technology to screen embryos have existed.

...

19 Nov
'Don't Give Up:' Parents' Intuition Spots a Rare Illness Before Doctors Do

'Don't Give Up:' Parents' Intuition Spots a Rare Illness Before Doctors Do

Parents usually know their child better than anyone, and if a parent suspects something is wrong, it probably is.

That was the case for Dan and Laura Wallenberg from Columbus, Ohio. EV Wallenberg was just 5 months old when they noticed that their daughter wasn't eat...

01 Nov
Drug Trio Could Give Patients With Cystic Fibrosis a New Option

Drug Trio Could Give Patients With Cystic Fibrosis a New Option

A three-drug combo that significantly improves lung function in cystic fibrosis patients could benefit 90% of people with the life-threatening disease, a new study suggests.

It included patients with a single copy of the most common genetic mutation for the disea...

22 Oct
FDA Approves New Drug for Most Common Form of Cystic Fibrosis

FDA Approves New Drug for Most Common Form of Cystic Fibrosis

A new drug to treat most cystic fibrosis patients has been approved by the U.S. Food and Drug Administration.

Trikafta (elexacaftor/ivacaftor/tezacaftor) is the first triple combination therapy available to treat patients with the most common cystic fibrosis mutation...

13 Sep
For This Mom, Rare Bone Disease Is a Family Affair

For This Mom, Rare Bone Disease Is a Family Affair

Most people expect some risk in activities like mountain biking or rollerblading, but few would expect to end up in the emergency room with a broken thigh bone from doing a squat.

That's exactly what happened to Rachael Jones, 39, who was just trying to stay in shap...

20 Aug
U.S. Task Force Updates Breast Cancer Gene Testing Recommendations

U.S. Task Force Updates Breast Cancer Gene Testing Recommendations

Mutations in two genes -- BRCA1 and BRCA2 -- are known to significantly increase the risk of breast cancer, but experts have long debated which women should be tested for them.

New recommendations from the U.S. Preventive Services Task Force (USPSTF) may help clarif...

13 Aug
Lots of Gluten During Toddler Years Might Raise Odds for Celiac Disease

Lots of Gluten During Toddler Years Might Raise Odds for Celiac Disease

Too much white bread and pasta fed to at-risk kids under age 5 could increase their odds of developing celiac disease, a new international study has concluded.

Every extra daily gram of gluten a young child eats increases their risk of celiac disease, if they are genet...

20 Jun
How Do Birth Defects Affect Childhood Cancer Risk?

How Do Birth Defects Affect Childhood Cancer Risk?

Children with birth defects may be at increased risk for childhood cancer, a new study finds.

Researchers analyzed data from more than 10 million children born in Texas, Arkansas, Michigan and North Carolina between 1992 and 2013.

Compared to children witho...

04 Jun
Is MRI Screening Worth It for Breast Cancer Survivors?

Is MRI Screening Worth It for Breast Cancer Survivors?

Breast MRI screening is a good way to detect small tumors, but it's unclear how much it benefits women with a history of breast cancer, a new study finds.

Right now, experts recommend that breast cancer survivors have yearly mammograms to help catch any recurrences e...